Package: LDAcoop Type: Package Title: Analysis of Data from Limiting Dilution Assay (LDA) with or without Cellular Cooperation Version: 0.1.2 Authors@R: c( person("Daniel", "Samaga", email = "daniel.samaga@helmholtz-munich.de", role = c("cre","aut")), person("Nikko", "Brix", role = "aut"), person("Benedek","Danko", role = "aut"), person("Kirsten", "Lauber", role = "aut"), person("Horst", "Zitzelsberger", role = "aut")) Maintainer: Daniel Samaga URL: https://github.com/ZytoHMGU/LDAcoop BugReports: https://github.com/ZytoHMGU/LDAcoop/issues Description: Cellular cooperation compromises the established method of calculating clonogenic activity from limiting dilution assay (LDA) data. This tool provides functions that enable robust analysis in presence or absence of cellular cooperation. The implemented method incorporates the same cooperativity module to model the non-linearity associated with cellular cooperation as known from the colony formation assay (Brix et al. (2021) : "Analysis of clonogenic growth in vitro." Nature protocols). License: GPL-3 Encoding: UTF-8 LazyData: true RoxygenNote: 7.2.3 Depends: R (>= 3.5.0) Imports: Hmisc Suggests: knitr, rmarkdown, testthat (>= 3.0.0) VignetteBuilder: knitr Config/testthat/edition: 3 Config/pak/sysreqs: cmake make libicu-dev libuv1-dev Repository: https://zytohmgu.r-universe.dev Date/Publication: 2024-07-17 09:45:49 UTC RemoteUrl: https://github.com/zytohmgu/ldacoop RemoteRef: HEAD RemoteSha: 40241733f63b169ab4d62db271ce13258011b4cd NeedsCompilation: no Packaged: 2026-10-04 07:41:25 UTC; root Author: Daniel Samaga [cre, aut], Nikko Brix [aut], Benedek Danko [aut], Kirsten Lauber [aut], Horst Zitzelsberger [aut]